Properties of cyclic AMP-independent catabolite gene activator proteins of Escherichia coli.

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Properties of cyclic AMP-independent catabolite gene activator proteins of Escherichia coli.

The protein products of two crp alleles encoding mutationally altered catabolite gene activator proteins CAP and CAPc, which are functionally active in vivo in the absence of cAMP, were purified by an immunoaffinity purification procedure. These proteins bind cAMP with the same affinity as does the wild-type catabolite gene activator protein. From their susceptibility to the proteolytic enzyme ...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1986

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)67291-6